APOMORPHINE相关论文
Food hoarding disturbances and altered Fos expression in male Mongolian gerbils (Meriones unguiculat
Male Mongolian gerbils have been found to exhibit a bimodal expression of food hoarding during food deprivation, with no......
Preparation Characterization and PK/PD Evaluation of Apomorphine-HCl Loaded Solid Lipid Nanoparticle
Apomorphine-HCl is a potent D1 and D2 dopamine receptor agonist,which is effective in the treatment of Parkinsonism for ......
Dysfunctional autophagy often occurs during the development of neurodegenerative diseases,such as Parkinson’s disease,H......
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AIM: To establish a new, reliable vomit model of minks.METHODS: Adult male minks were randomly divided into 8 groups (n=......
Dysfunctional autophagy often occurs during the development of neurodegenerative diseases, such as Parkinson’s disease,......
Aim: (-)Stepholidine (SPD) is an active ingredient of the Chinese herb Stephania intermedia, which binds to the dopamine......
目的 利用阿扑吗啡和旋转T迷宫装置,观察阿扑吗啡对大鼠视觉线索辨别学习和逆反学习的影响.方法 首先通过食物奖励与灯光线索的结......
目的 观察青春期(出生后38～51 d)阿扑吗啡注射对大鼠精神相关行为的影响.方法 以Wistar大鼠为实验对象,利用大鼠穿梭程序自动控制仪......
AIM:To characterize the gastric myoelectric activity(GMA) and intra-abdominal pressure changes induced by emetic stimuli......
目的 探讨多巴胺受体激动剂-阿扑吗啡对大鼠视觉辨别学习和工作记忆的影响.方法利用旋转T迷宫装置,通过食物强化,分别训练大鼠正常......
目的 经多巴胺能系统亢进的方法建立并评价拟抽动秽语综合征小鼠模型.方法经硫酸苯丙胺3 mg/kg单次腹腔注射和阿朴吗啡2 mg/kg单次......
目的应用阿朴吗啡(APO)诱导大鼠阴茎勃起模型,探讨抗雄激素对阴茎勃起功能的影响及其可能机制.方法 SD雄性成年大鼠随机分为3组,伪......
<正> 1 Introduction At the spinal level, the dopaminergic, the α_1 adrenergic and the neurokinin receptors play definit......
目的探讨线刀损毁内侧前脑束建立的帕金森病模型大鼠行为学改变与黒质致密部多巴胺能神经元存活率之间的相关性。方法采用可伸缩线......
目的：观察6-羟基多巴胺（6-hydroxydopamine，6-OHDA）毁损黑质DA能神经元后，不同时间点腹腔注射阿朴吗啡（Apomorphine，APO）大鼠行为学及中脑......
研究左旋四氢巴马汀(L-tetrahydropalmatine,L-THP)对哺乳期催乳素(Prolactin,PRL)水平低下模型大鼠中枢多巴胺(Dopamine,DA)D2受......
目的:探讨应用安雄进行雄激素替代对去势大鼠勃起功能的影响.方法:取40只成年雄性SD大鼠,分为去势、高、低剂量安雄及假手术4组.治......
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ｓＧｎＲＨ同时刺激离体灌流孵育的鲤鱼脑垂体ＧｔＨ和ＧＨ分泌，ＧｔＨ和ＧＨ对ｓＧｎＲＨ脉冲式刺激的分泌反应的时间进程和剂量依存关系相似。生长抑素显著抑制基础的ｓＧｎＲＨ刺激的......
在用左旋多巴（ｌｅｖｏｄｏｐａ）治疗帕金森病的长期过程中，许多患者都受到长期用药所致的运动障碍副作用的困扰．这种药物反应很可能反映了由于长期受药......
目的探讨不同时间点阿朴吗啡（APO）腹腔注射6-OHDA所致帕金森病模型大鼠的行为学及中脑腹侧被盖区（VTA）形态学变化。方法6-OHDA单侧一点......
Parkinson’s disease(PD) is a chronic debilitating disease affecting approximately 1% of the population over the age of ......
Involvement of CRH Receptors in the Neuroprotective Action of R-Apomorphine in the Striatal 6-OHDA R
The dopamine D1-D2 receptor agonist, R-apomorphine, has been shown to be neuroprotective in different models of Parkinso......
Apomorphine 是D1/ D2受体激动剂，现在用于治疗parkinsonian病。已有的研究发现apomorphine 能够协同BDNF (brain-derived neurotro......
